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CDC

Lipoxygenase inhibitor
 
BML-EI211-0010 10 mg 87.00 USD
 
BML-EI211-0050 50 mg 359.00 USD
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Selective 12-lipoxygenase inhibitor. IC50=0.063 µM, 3.33 µM and 1.89 µM for 12-, 15- and 5-LO respectively in isolated enzyme preparations.

Product Specification

MW:321.3
 
CAS:132465-11-3
 
Purity:≥98%
 
Solubility:Soluble in ethanol (5mg/ml) or DMSO (5mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store, as supplied, at room temperature for up to 1 year. Store under nitrogen after opening. Product is subject to oxidation. Make solutions fresh daily.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis: J. Chan, et al.; FASEB J. 32, 3816 (2018), Application(s): Inhibition of 12(S)-HETE biosynthesis in mice, Abstract;
Mechanisms underlying increased reactivity of pulmonary arteries contralateral to a localized high-flow anastomosis: S. Pfister, et al.; J. Thorac. Cardiovasc. Surg. 141, 425 (2011), Abstract; Full Text

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