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A-3

PKA inhibitor
 
BML-EI145-0010 10 mg 84.00 USD
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Replaces Prod. #: ALX-270-039

Inhibitor of cAMP- and cGMP-dependent protein kinase (PKA, Ki=4.3µM and PKG, Ki=3.8µM), protein kinase C (PKC, Ki=47µM), casein kinase I and II, and myosin light chain kinase (MLCK, Ki=7.4µM).

Product Specification

Formula:C12H13ClN2O2S . HCl
 
MW:284.8 . 36.5
 
CAS:78957-85-4
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water (50mg/ml), DMSO (50mg/ml) or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Note: Product is not sterile.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways: J. Midkiff, et al.; PLoS One 6, e25395 (2011), Abstract; Full Text
Naphthalenesulfonamides as calmodulin antagonists and protein kinase inhibitors: M. Inagaki, et al.; Mol. Pharmacol. 29, 577 (1986), Abstract;

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