Dual lipoxygenase (IC50=24 µM) and cyclooxygenase (IC50=11.8 µM) inhibitor.
Product Details
Alternative Name: | 1-Phenyl-3-pyrazolidinone |
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Formula: | C9H10N2O |
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MW: | 162.2 |
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CAS: | 92-43-3 |
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Purity: | ≥97% (TLC) |
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Identity: | Determined by IR. |
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Appearance: | White to off-white solid. |
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Solubility: | Soluble in DMSO (75 mg/ml) or ethanol (25 mg/ml warm). |
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Shipping: | Ambient |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones: D. L. Flynn, et al.; Prostaglandins Leukot. Med.
22, 357 (1986),
Abstract;