Suicide inhibitor of LTA4 hydrolase. Biosynthesis from Mead acid via 5-lipoxygenase.
Product Details
| Alternative Name: | LTA3-ME |
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| Formula: | C21H34O3 |
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| MW: | 334.5 |
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| CAS: | 83851-38-1 |
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| Concentration: | 50µg/ml |
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| Formulation: | Oil dissolved in hexane containing 2% triethylamine. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Colorless liquid. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Use/Stability: | Store as supplied (-80°C) for up to one year. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Mechanism-based inactivation of leukotriene A4 hydrolase during leukotriene B4 formation by human erythrocytes: L. Orning, et al.; J. Biol. Chem.
265, 14911 (1990),
Abstract;
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Leukotriene A3. A poor substrate but a potent inhibitor of rat and human neutrophil leukotriene A4 hydrolase: J. F. Evans, et al.; J. Biol. Chem.
160, 10966 (1985),
Abstract;
Full Text
