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Leukotriene B4-dimethylamide

Prostanoid receptor ligand
BML-EI102-0050 50 µg 439.00 USD
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Leukotriene B4 antagonist. Inhibits binding of [3H]-LTB4 to guinea pig lung membranes (Ki=0.13 µM). Antagonizes the degranulation response to LTB4 in rabbit PMNL (Kd=0.2 µM) acting, most likely, via receptor desensitization. Partial agonist at higher concentrations (5 µM).

Product Details

Concentration:50 µg/ml
Formulation:Solution in ethanol.
Purity:≥98% (HPLC)
Shipping:Dry Ice
Long Term Storage:-80°C
Use/Stability:Store as supplied (-80°C) for up to two years.
Regulatory Status:RUO - Research Use Only
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Product Literature References

Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents: R. C. Falcone & D. Aharony, et al.; J. Pharmacol. Exp. Ther. 155, 565 (1990), Abstract;