Replaces Prod. #: ALX-550-049
Potent glutamate receptor agonist. Displays full agonist activity at mGlu1 and mGlu5.
Product Details
| Alternative Name: | α-Amino-3-hydroxy-5-isoxazoleacetic acid |
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| Formula: | C5H6N2O4 |
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| MW: | 158.1 |
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| CAS: | 2552-55-8 |
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| Purity: | ≥98% (HPLC) |
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| Identity: | Determined by 1H-NMR and MS. |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water (20mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury: C. Descloux, et al.; Cell Death Dis.
9, 853 (2018),
Abstract;
Full Text
Excitatory amino acid receptors in the vertebrate central nervous system: G.L. Collingridge & R.A. Lester; Pharmacological Rev.
40, 143 (1989),
Abstract;
Intrahippocampal injections of ibotenic acid provide histological evidence for a neurotoxic mechanism different from kaianic acid: C. Kohler et al.; Neurosci. Lett.
15, 223 (1979),
Abstract;
