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Bicuculline methobromide

GABA receptor antagonist and K+ channel blocker
 
BML-EA109-0050 50 mg 200.00 USD
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Replaces Prod. #: ALX-550-040

GABAA receptor antagonist.Blocks Ca2+-activated K+ channels.

Product Details

Formula:C21H20BrNO6
 
MW:462.3
 
Source:Synthetic.
 
CAS:73604-30-5
 
Purity:≥98%
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water (25mg/ml).
 
Shipping:Ambient Temperature
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
Handling:Protect from light.
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

P2X7-dependent constitutive Interleukin-1β release from pyramidal neurons of the normal mouse hippocampus: Evidence for a role in maintenance of the innate seizure threshol: S.S. Dutta, et al.; Neurobiol. Dis. 168, 105689 (2022), Abstract;
3H-baclofen and 3H-GABA bind to biculline-insensitive GABA B sites in rat brain.: D.R. Hill & N.G. Bowery; Nature 290, 1949 (1981), Abstract;

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