NMDA agonist/antagonist. Synaptic depressant.
Product Specification
| Alternative Name: | DL-2-Amino-4-phosphonobutanoic acid |
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| Formula: | C4H10NO5P |
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| MW: | 183.1 |
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| CAS: | 6323-99-5 |
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| Purity: | ≥99% (TLC) |
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| Identity: | Determined by NMR. |
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| Appearance: | White solid. |
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| Solubility: | Soluble in water (25mg/ml) or in dilute aqueous base. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | Ambient |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra: G. De Sarro, et al.; Eur. J. Pharmacol.
106, 175 (1984),
Abstract;
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord: J. Davies & J.C. Watkins; Brain Res.
235, 378 (1982),
Abstract;
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations: R.H. Evans, et al.; Br. J. Pharmacol.
75, 65 (1982),
Abstract;
2-amino-4-phosphonobutyric acid: a new pharmacological tool for retina research: M.M. Slaughter & R.F. Miller; Science
211, 182 (1981),
Abstract;
Micromolar L-2-amino-4-phosphonobutyric acid selectively inhibits perforant path synapses from lateral entorhinal cortex: J.F. Koerner & C.W. Cotman; Brain Res.
216, 192 (1981),
Abstract;
Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog: R.H. Evans, et al.; Br. J. Pharmacol.
67, 591 (1979),
Abstract;
