Produces a dose-dependent hyperalgesia. Stereospecifically sensitizes C-fiber mechanoheat nociceptors.
Product Details
| Alternative Name: | 8(R),15(S)-DiHETE |
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| Formula: | C20H32O4 |
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| MW: | 336.5 |
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| CAS: | 80234-67-9 |
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| Concentration: | 50 µg/ml |
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| Formulation: | Oil dissolved in ethanol. |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | Liquid. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The 15-lipoxygenase product, 8R,15S-diHETE, stereospecifically sensitizes C-fiber mechanoheat nociceptors in hairy skin of rat: D.M. White, et al.; J. Neurophysiol.
63, 966 (1990),
Abstract;
Hyperalgesic properties of 15-lipoxygenase products of arachidonic acid: J.D. Levine, et al.; Proc. Natl. Acad. Sci. USA
83, 5331 (1986),
Abstract;
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