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8(R),15(S)-Dihydroxyeicosa-5Z,9E,11E,13E-tetraenoic acid (DiHETE)

 
BML-DTR815-0050 50 µg 210.00 USD
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Produces a dose-dependent hyperalgesia. Stereospecifically sensitizes C-fiber mechanoheat nociceptors.

Product Details

Alternative Name:8(R),15(S)-DiHETE
 
Formula:C20H32O4
 
MW:336.5
 
CAS:80234-67-9
 
Concentration:50 µg/ml
 
Formulation:Oil dissolved in ethanol.
 
Purity:≥99% (HPLC)
 
Appearance:Liquid.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Regulatory Status:RUO - Research Use Only
 
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Product Literature References

The 15-lipoxygenase product, 8R,15S-diHETE, stereospecifically sensitizes C-fiber mechanoheat nociceptors in hairy skin of rat: D.M. White, et al.; J. Neurophysiol. 63, 966 (1990), Abstract;
Hyperalgesic properties of 15-lipoxygenase products of arachidonic acid: J.D. Levine, et al.; Proc. Natl. Acad. Sci. USA 83, 5331 (1986), Abstract; Full Text

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