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5(S),6(R)-Dihydroxyeicosa-7E,9E,11Z,14Z-tetraenoic acid (DiHETE)

Prostanoid receptor ligand
BML-DS056-0050 50 µg 280.00 USD
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Synthesis via enzymatic and nonenzymatic hydrolysis of LTA4. Induces contraction of guinea pig lung parenchymal strips. Partial agonist at LTD4 receptors. Potent inhibitor of LTB4 induced neutrophil migration (IC50 = 8nM).

Product Details

Alternative Name:5(S),6(R)-DiHETE
Formulation:Oil dissolved in ethanol.
Purity:≥99% (HPLC)
Appearance:Colorless liquid.
Shipping:Dry Ice - Dangerous Good
Long Term Storage:-80°C
Regulatory Status:RUO - Research Use Only
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Product Literature References

Comparative biological activities of the four synthetic (5,6)-dihete isomers: A. Muller, et al.; Prostaglandins 38, 635 (1989), Abstract;
Comparative activity of natural mono-, di- and tri-hydroxy derivatives of arachidonic acid on guinea-pig lungs: myotropic effect and stimulation of cyclooxygenase activity: P. Sirois, et al.; Prostaglandins 24, 405 (1982), Abstract;

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