Human dishevelled-1 [Cys+557-571]. Suitable blocking peptide for polyclonal antiserum to dishevelled-1 (BML-DA4170).
Product Details
| Sequence: | H-Cys-Ser-Arg-Arg-Ala-Pro-Gly-Arg-Glu-Lys-Glu-Arg-Arg-Ala-Ala-Gly-OH |
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| MW: | 1799.4 |
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| Purity: | ≥80% (HPLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in water and aqueous buffers. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-jun terminal kinase: A. Mudher, et al.; J. Neuroscience.
21, 4987 (2001),
Abstract;
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Dishevelled-1 regulates microtubule stability: a new function mediated by glycogen synthase kinase-3beta: O. Krylova, et al.; J. Cell Biol.
151, 83 (2000),
Abstract;
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Structural basis of the recognition of the dishevelled DEP domain in the Wnt signaling pathway: H.C. Wong, et al.; Nature Struct. Biol.
7, 1178 (2000),
Abstract;
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells: L. Li, et al.; J. Biol. Chem.
274, 129 (1999),
Abstract;
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DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability: S. Kishida, et al.; Mol. Cell Biol.
19, 4414 (1999),
Abstract;
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Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization: F. Fagotto, et al.; J. Cell Biol.
145, 741 (1999),
Abstract;
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Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability : H. Yamamoto, et al.; J. Biol. Chem.
274, 10681 (1999),
Abstract;
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cDNA cloning of a human dishevelled DVL-3 gene, mapping to 3q27, and expression in human breast and colon carcinomas: T.D. Bui, et al.; Biochem. Biophys. Res. Commun.
239, 510 (1997),
Abstract;
Human dishevelled genes constitute a DHR-containing multigene family: M.V. Semenov & M. Snyder; Genomics
42, 302 (1997),
Abstract;
Overexpression of the mouse dishevelled-1 protein inhibits GSK-3beta-mediated phosphorylation of tau in transfected mammalian cells: U. Wagner, et al.; FEBS Lett.
411, 369 (1997),
Abstract;
cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene: A. Pizzuti, et al.; Hum. Molec. Genet.
5, 953 (1996),
Abstract;
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Genomic organization of mouse dishevelled genes. : Y.S. Yang, et al.; Gene
180, 121 (1996),
Abstract;
Interaction between Wingless and Notch signaling pathways mediated by dishevelled: J.D. Axelod, et al.; Science
271, 1826 (1996),
Abstract;
Isolation and characterization of mouse dishevelled-3: M. Tsang, et al.; Dev. Dyn.
207, 253 (1996),
Abstract;
Organization and promoter analysis of the mouse dishevelled-1 gene: N. Lijam & D.J. Sussman; Genome Res.
5, 116 (1995),
Abstract;
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Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled: D.J. Sussman, et al.; Dev. Biol.
166, 73 (1994),
Abstract;
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