| BML-CR3320-0025 | 25 µl | 122.00 USD |  |
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| Alternative Name: | CYP3A2 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of C-terminal rat CYP3A21. |
| UniProt ID: | P05183 |
| Species reactivity: | Rat |
| Specificity: | Recognizes rat CYP3A2. Not suitable for use on human tissue. |
| Applications: | IHC (FS), IHC (PS), WB |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Members of the cytochrome P-450 3A (CYP3A) sub-family catalyze the 6β-hydroxylation of testosterone, and the metabolism of a number of drugs such as cyclosporin A (Prod. No. BML-A195), and warfarin. They are inducible by glucocorticoids such as dexamethasome (Prod. No. BML-EI126) and by macrolide antibiotics such as erythromycin and pregnenolone 16α-carbonitrile (U-14975, PCN) (Prod. No. BML- S620). Rat CYP3A1 and CPY3A2 share 89% sequence similarity at the amino acid level and are predominantly located in the liver, principally in the centrilobular region. PCN induces CYP3A1/2 gene expresion in regions of the liver. |
| Regulatory Status: | RUO - Research Use Only |
Dexamethasone |
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| Glucocorticoid receptor ligand | ||||||
| 50-02-2, ≥98% (HPLC) | Print as PDF | ||||||
| BML-EI126-0001 | 1 g | 75.00 USD | |
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| BML-EI126-0005 | 5 g | 350.00 USD | |
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Cyclosporin A |
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| Immunosuppressant | ||||||
| 59865-13-3, Isolated from Fusarium solani, ≥98% (Assay) | Print as PDF | ||||||
| BML-A195-0100 | 100 mg | 64.00 USD | |
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| BML-A195-0500 | 500 mg | 260.00 USD | |
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Pregnenolone-16α-carbonitrile |
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| Cytochrome P450 inducer | ||||||
| 1434-54-4, ≥99% (HPLC) | Print as PDF | ||||||
| BML-S620-0020 | 20 mg | 48.00 USD | |
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| BML-S620-0100 | 100 mg | 207.00 USD | |
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