| Alternative Name: | CYP2E1 |
| |
| Host: | Sheep |
| |
| Immunogen: | Synthetic peptide corresponding to the C-terminus of hepatic human, rat, rabbit, and mouse CYP2E1. |
| |
| UniProt ID: | P05181 (human), Q05421 (mouse), P05182 (rat), P08682 (rabbit) |
| |
| Species reactivity: | Human, Mouse, Rat
Rabbit
|
| |
| Specificity: | Recognizes CYP2E1. |
| |
| Applications: | IHC, WB
|
| |
| Blocking Peptide: | For Blocking peptide see Prod. No. BML-CP0270.
|
| |
| Formulation: | Liquid. Serum containing 0.01% sodium azide. |
| |
| Handling: | Avoid freeze/thaw cycles. Aliquot undiluted antibody into smaller volumes prior to freezing if appropriate. Store diluted antibody at +4°C and use within one month. |
| |
| Shipping: | Shipped on Blue Ice |
| |
| Long Term Storage: | -20°C |
| |
| Scientific Background: | Cytochrome P-450 2E1 (CYP2E1) is principally found in the liver, and is ethanol-inducible. It catalyses many biotransformations. In rat brain CYP2E1 is localized to cells within the substantia nigra and in striatial blood vessels where a possible role in the pathology of oxidative stress, believed to underlie nigral degeneration has been proposed. |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
