Human Chromogranin A [352-372, P370L]. One of the two known polymorphic variants of catestatin occurring in the human population.
Product Details
| Alternative Name: | [P370L]Chromogranin A (352-372) |
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| Sequence: | H-Ser-Ser-Met-Lys-Leu-Ser-Phe-Arg-Ala-Arg-Ala-Tyr-Gly-Phe-Arg-Gly-Pro-Gly-Leu-Gln-Leu-OH (human Chromogranin A[352-372, P370L]) |
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| Formula: | C105H168N32O27S1 |
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| MW: | 2342.8 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in Water. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology: G. Wen, et al.; Am. J. Hum. Genet.
74, 197 (2004),
Abstract;
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Formation of the catecholamine release-inhibitory peptide catestatin from chromogranin A. Determination of proteolytic cleavage sites in hormone storage granules: C. V. Taylor, et al.; J. Biol. Chem.
275, 22905 (2000),
Abstract;
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Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist: S. K. Mahata, et al.; J. Clin. Invest.
100, 1623 (1997),
Abstract;
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Secretion from chromaffin cells is controlled by chromogranin A-derived peptides: J. P. Simon, et al.; Proc. Natl. Acad. Sci. USA
85, 1712 (1988),
Abstract;
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The primary structure of human chromogranin A and pancreastatin: D. S. Konecki, et al.; J. Biol. Chem.
262, 17026 (1987),
Abstract;
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