A novel NO donor which only releases NO in the presence of thiols. It is a potent vasodilator and inhibitor of platelet aggregation.
Product Details
| Alternative Name: | 4-Phenyl-3-furoxancarbonitrile |
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| Formula: | C9H5N3O2 |
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| MW: | 187.2 |
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| CAS: | 125520-62-9 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | White solid. |
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| MeltingPoint: | 72-74°C |
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| Solubility: | Soluble in ethanol (25 mg/ml) or DMSO (25 mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A new class of furoxan derivatives as NO donors: mechanism of action and biological activity: R. Ferioli, et al.; Br. J. Pharmacol.
114, 816 (1995),
Abstract;
Full Text
Furoxans as nitric oxide donors. 4-Phenyl-3-furoxancarbonitrile: thiol-mediated nitric oxide release and biological evaluation: C. Medana, et al.; J. Med. Chem.
37, 4412 (1994),
Abstract;
