A potent uncoupler of mitochondrial oxidative phosphorylation. CCCP is a useful tool for depolarizing mitochodrial membrane potential.
Product Details
| Alternative Name: | (3-Chlorophenyl)hydrazonomalonitrile |
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| Formula: | C9H5ClN4 |
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| MW: | 204.6 |
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| CAS: | 555-60-2 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Determined by IR. |
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| Appearance: | Yellow-orange solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Depolarization evokes different patterns of calcium signals and exocytosis in bovine and mouse chromaffin cells: the role of mitochondria: E. Ales, et al.; Eur. J. Neurosci.
21, 142 (2005),
Abstract;
Mechanisms of diethylstilbestrol-induced calcium movement in MG63 human osteosarcoma cells: Y.-C. Chen, et al.; Toxicol. Lett.
122, 245 (2001),
Abstract;
General Literature References
Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria: A. A. Gerencser, et. al.; J. Physiol.
590, 2845 (2012),
Abstract;
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