cADPR antagonist. Blocks the cADPR-induced release of Ca2+ from sea urchin egg homogenates at 1-3.5 µM.
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Product Details
Formula: | C15H20BrN5O13P2 |
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MW: | 620.2 |
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CAS: | 151898-26-9 |
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Purity: | ≥95% |
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Appearance: | White powder. |
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Solubility: | Soluble in water (5mg/ml). |
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Shipping: | Ambient |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Selective inhibitors of SARM1 targeting an allosteric cysteine in the autoregulatory ARM domain: H.C. Feldman, et al.; PNAS
119, e2208457119 (2022 ),
Abstract;
Synthesis and characterization of antagonists of cyclic-ADP-ribose-induced Ca2+ release: T. F. Walseth & H. C. Lee; Biochim. Biophys. Acta
1178, 235 (1993),
Abstract;