A potent irreversible inactivator of calmodulin. Possesses potent antiproliferative and cytotoxic activity. It is also an irreversible D2 dopamine receptor antagonist.
Product Details
| Alternative Name: | SKF-7171A |
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| Formula: | C22H25CIF3N3S . 2HCl |
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| MW: | 528.6 |
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| CAS: | 83016-35-7 |
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| Purity: | ≥98% |
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| Appearance: | Pale yellow solid. |
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| Solubility: | Soluble in DMSO (50mg/ml) or water (10mg/ml warm). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Dual action of ketamine confines addiction liability: L.D. Simmler, et al.; Nature
608, 368 (2022),
Abstract;
Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells: G.B. Manoharan, et al.; PLoS One
17, e0268635 (2022),
Abstract;
