Replaces Prod. #: ALX-270-151
Binds to calmodulin, inhibiting Ca2+-calmodulin-regulated enzyme activity. Cell permeable.
Product Details
| Alternative Name: | N-(6-Aminohexyl)-1-naphthalenesulfonamide . HCl |
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| Formula: | C16H22N2O2S . HCl |
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| MW: | 342.9 |
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| CAS: | 61714-25-8 |
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| Purity: | ≥98% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water, DMSO (20mg/ml), 100% ethanol (hot) or methanol (hot). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Stable for at least 1 year after receipt when stored at room temperature. Stock solutions are stable for for up to 6 months at -20°C. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation : H. Hidaka, et al.; PNAS
78, 4354 (1981),
Abstract;
Full Text
[Pharmacology of calmodulin: calmodulin antagonist (author's transl)]: H. Hidaka; Prot. Nucl. Acid Enz.
26 , 977 (1981),
Abstract;
Hydrophobic regions function in calmodulin-enzyme(s) interactions.: T. Tanaka & H. Hidaka ; J. Biol. Chem.
255, 11078 (1980),
Abstract;
Full Text
