A potent, selective, cell-permeable calmodulin antagonist. It inhibits calmodulin-dependent enzymes such as MLC kinase (IC50=8 µM) and phosphodiesterase I (IC50=0.53 µM).
Product Details
| Formula: | C44H43N3O9 |
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| MW: | 757.8 |
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| CAS: | 114784-59-7 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Yellow solid. |
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| Solubility: | Soluble in DMSO (25 mg/ml) or ethanol (25 mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Interleukin-1β processing is dependent upon a calcium-mediated interaction with calmodulin: J.S. Ainscough, et al.; J. Biol. Chem.
290, 31151 (2015),
Application(s): Cell culture,
Abstract;
Full Text
Interaction of berbamine compound E6 and calmodulin-dependent myosin light chain kinase: Z.-Y. Hu, et al.; Biochem. Pharmacol.
44, 1543 (1992),
Abstract;
