A potent and selective TRPA1 inhibitor.
Product Details
Formula: | C18H21N5O3 |
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MW: | 355.4 |
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CAS: | 349085-38-7 |
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Purity: | ≥98% (HPLC) |
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Appearance: | White solid. |
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Solubility: | Soluble in DMSO (25 mg/ml). |
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Shipping: | Ambient Temperature |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Adjuvant effect of an alternative plasticizer, diisopropyl adipate, on a contact hypersensitivity mouse model: link with sensory ion channel TRPA1 activation: K. Kurohane, et al.; Biol. Pharm. Bull.
38, 1054 (2015),
Application(s): Cell Culture,
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Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1): T. E. Taylor-Clark, et al.; Mol. Pharmacol.
73, 274 (2008),
Abstract;
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TRPA1 mediates formalin-induced pain: C. R. McNamara, et al.; Proc. Natl. Acad. Sci. USA
104, 13525 (2007),
Abstract;
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