Blocks cyclic nucleotide-gated calcium channels.
Product Details
| Formula: | C22H26N2O4S . HCl |
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| MW: | 451.0 |
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| CAS: | 42399-54-2 |
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| Purity: | ≥98% |
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| Appearance: | White powder. |
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| Solubility: | Soluble in water (>10mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store solutions at -20ºC for up to 1 month. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR: J. Huang, et al.; PNAS
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Abstract;
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Cyclic nucleotide phosphodiesterase 1 regulates lysosome-dependent type I collagen protein degradation in vascular smooth muscle cells: Y. Cay, et al.; Arterioscler. Thromb. Vasc. Biol.
31, 616 (2011),
Abstract;
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A new subunit of the cyclic nucleotide-gated cation channel in retinal rods: T. Y. Chen, et al.; Nature
362, 764 (1993),
Abstract;
A derivative of amiloride blocks both the light-regulated and cyclic GMP-regulated conductances in rod photoreceptors: G. D. Nicol, et al.; J. Gen. Physiol.
90, 651 (1987),
Abstract;
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