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L-cis-Diltiazem HCl

Ca2+ channel blocker
BML-CA207-0005 5 mg 117.00 USD
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Blocks cyclic nucleotide-gated calcium channels.

Product Details

Formula:C22H26N2O4S . HCl
Appearance:White powder.
Solubility:Soluble in water (>10mg/ml).
Long Term Storage:Ambient
Use/Stability:Store solutions at -20ºC for up to 1 month.
Regulatory Status:RUO - Research Use Only
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Product Literature References

The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR: J. Huang, et al.; PNAS 117, 28485 (2020), Abstract; Full Text
Cyclic nucleotide phosphodiesterase 1 regulates lysosome-dependent type I collagen protein degradation in vascular smooth muscle cells: Y. Cay, et al.; Arterioscler. Thromb. Vasc. Biol. 31, 616 (2011), Abstract; Full Text
A new subunit of the cyclic nucleotide-gated cation channel in retinal rods: T. Y. Chen, et al.; Nature 362, 764 (1993), Abstract;
A derivative of amiloride blocks both the light-regulated and cyclic GMP-regulated conductances in rod photoreceptors: G. D. Nicol, et al.; J. Gen. Physiol. 90, 651 (1987), Abstract; Full Text

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