Benzodiazepine antagonist. Reverses all the effects of benzodiazepine agonists and inverse agonists.
Product Details
Alternative Name: | Ro 15-1788 |
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Formula: | C15H14FN3O3 |
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MW: | 303.3 |
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CAS: | 78755-81-4 |
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Purity: | ≥98% (Assay) |
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Appearance: | White crystalline powder. |
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Solubility: | Soluble in ethanol (5 mg/ml warm) or DMSO (25 mg/ml warm) |
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Shipping: | Ambient Temperature |
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Long Term Storage: | Ambient |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Reduction of reticulata neuronal activity by zolpidem and alpidem, two imidazopyridines with high affinity for type I benzodiazepine receptors: G. Mereu, et al.; Eur. J. Pharmacol.
179, 339 (1990),
Abstract;
Chronic treatment with Ro 15-1788 distinguishes between its benzodiazepine antagonist, agonist and inverse agonist properties: S. E. File, et al.; Neuropharmacol.
89, 113 (1986),
Abstract;