This fluorogenic peptide is often the substrate of choice for assaying the trypsin-like activity of purified proteasomes. Benefits include a low Km, high specific activity, and the fact that the substrate is cleaved exclusively at the R-AMC bond.
Product Details
| Alternative Name: | Ac-RLR-AMC |
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| Sequence: | Ac-Arg-Leu-Arg-AMC |
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| Formula: | C30H46N10O6 |
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| MW: | 642.7 |
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| Formulation: | Lyophilized. |
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| Purity: | ≥97% (HPLC) |
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| Appearance: | Solid. |
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| Solubility: | Soluble in DMSO, methanol or aqueous solutions. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Several substrates with R-AMC scissile bonds can be used for assaying trypsin-like activity. One such substrate is Ac-Arg-Leu-Arg-AMC, which benefits from a low Km, high specific activity and the fact that it is cleaved exclusively at the R-AMC bond. This fluorogenic peptide is often the substrate of choice for assaying the trypsin-like activity of purified proteasomes. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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Full Text
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