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BML-AW9560-0005 5 mg 922.00 USD
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Highly specific substrate for the caspase-like peptidic activity of the 20S proteasome.

Product Details

Alternative Name:Ac-GPLD-AMC
Sequence:Ac-GPLD-AMC, Fluorogenic Substrate
Purity:≥98% (HPLC)
Appearance:White solid.
Solubility:Soluble in 20% aqueous acetic acid (1mg/ml).
Shipping:Blue Ice
Long Term Storage:-20°C
Use/Stability:Store solutions at or below -20°C for up to 3 months
Regulatory Status:RUO - Research Use Only

Product Literature References

Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer's Disease Model: N.K. Lee, et al.; Sci. Rep. 7, 39340 (2017), Abstract; Full Text
Proteasome properties of hemocytes differ between the whiteleg shrimp Penaeus vannamei and the brown shrimp Crangon crangon (Crustacea, Decapoda): S. Gotze, et al.; Cell Stress Chaperones 22, 879 (2017), Abstract; Full Text
The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System: A.C.D. Fuchs, et al.; Structure 25, 834 (2017), Abstract; Full Text
Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure: D.S. Pitcher, et al.; EBioMedicine 2, 642 (2015), Application(s): Fluorescence, Abstract;
BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch: M. Minoia, et al.; Autophagy 10, 1603 (2014), Abstract; Full Text
The proteasomes of two marine decapod crustaceans, European lobster (Homarus gammarus) and Edible crab (Cancer pagurus), are differently impaired by heavy metals: S. Gotze, et al.; Comp. Biochem. Physiol. C Toxicol. Pharmacol. 162, 62 (2014), Abstract;
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites: A. F. Kisselev, et al.; J Biol. Chem. 278, 35869 (2003), Abstract; Full Text

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Proteasome 20S
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Proteasome 20S Substrate
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