α2-Adrenergic receptor agonist. Displays affinity for the I1-imidazoline receptor. Spasmolytic activity.
Product Details
| Formula: | C9H8ClN5S . HCl |
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| MW: | 290.2 |
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| CAS: | 64461-82-1 (hydrochloride) / 51322-75-9 (free base) |
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| Purity: | ≥99% (TLC) |
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| Appearance: | White solid. |
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| Solubility: | Soluble in water (20 mg/ml). |
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| Shipping: | Ambient |
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| Long Term Storage: | Ambient |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Tizanidine: neuropharmacology and mechanism of action: D. M. Coward, et al.; Neurology
44, S6 (1994),
Abstract;
Antinociceptive activity induced by tizanidine and alpha 2-adrenoreceptors: T. Nabeshima, et al.; Neuropharmacol.
26, 1453 (1987),
Abstract;
Comparison of alpha-adrenoceptor involvement in the antinociceptive action of tizanidine and clonidine in the mouse: T. Kameyama, et al.; Eur. J. Pharmacol.
125, 257 (1986),
Abstract;
