Centrally acting α2-adrenergic receptor agonist. In the guinea pig cerebral cortex, the Kd is 20 and 880 nM for the α2A- and the α2C-adrenoceptor, respectively. Antihypertensive agent.
Product Details
| Formula: | C9H9Cl2N3O . HCl |
| |
| MW: | 282.5 |
| |
| CAS: | 29520-14-7 / 29110-48-3 |
| |
| Purity: | ≥98% (HPLC) |
| |
| Appearance: | White solid. |
| |
| Solubility: | Soluble in water (25 mg/ml). |
| |
| Shipping: | Ambient Temperature |
| |
| Long Term Storage: | Ambient |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Please mouse over
Product Literature References
From alpha and beta to I1: an overview of sympathetic receptors involved in blood pressure control targets for drug treatment: P. A. van Zweiten, et al.; J. Cardiovasc. Pharmacol.
27, S5 (1996),
Abstract;
Comparison of the binding activities of some drugs on alpha 2A, alpha 2B and alpha 2C-adrenoceptors and non-adrenergic imidazoline sites in the guinea pig: S. Uhlen, et al.; Pharmacol. Toxicol.
76, 353 (1995),
Abstract;
