A QUANTIZYME® Assay System. The MMP-7 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-7 (MMP-7, matrilysin) using a quenched fluorogenic peptide: OMNIMMP® fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP-7, a potential therapeutic target. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH)3, and a detailed instruction booklet.
Product Details
| Alternative Name: | Matrilysin, Pump |
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| Applications: | Fluorescent detection, HTS
Activity assay
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Contents: | MMP-7 enzyme (human) (recombinant), substrate, calibration standard, inhibitor, assay buffer, 96-well white microplate. |
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| UniProt ID: | P09237 |
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| Regulatory Status: | RUO - Research Use Only |
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