Colorimetric substrates plus inhibitors to allow detection of multiple caspases. Absorbance is monitored at 405 nm.
Product Specification
| Applications: | Colorimetric detection, HTS
Activity assay
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Contents: | 1 mg each of Ac-DEVD-pNA, Ac-YVAD-pNA, Ac-IETD-pNA; 0.1 mg each of Ac-DEVD-CHO, Ac-YVAD-CHO, Ac-IETD-CHO; 1 mg p-nitroaniline. |
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| Technical Info/Product Notes: | Biocompare Article: Keep an Eye on Apoptosis with Caspase Assays |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Indomethacin sensitizes TRAIL-resistant melanoma cells to TRAIL-induced apoptosis through ROS-mediated upregulation of death receptor 5 and downregulation of survivin: A.K. Tse, et al.; J. Invest. Dermatol.
134, 1397 (2014),
Abstract;
The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction: E. Mavrommatis, et al.; Mol. Cell. Biochem.
381, 69 (2013),
Abstract;
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The herbal compound cryptotanshinone restores sensitivity in cancer cells that are resistant to the tumor necrosis factor-related apoptosis-inducing ligand: A.K. Tse, et al.; J. Biol. Chem.
288, 29923 (2013),
Abstract;
Full Text
A switch of G protein-coupled receptor binding preference from phosphoinositide 3-kinase (PI3K)-p85 to filamin A negatively controls the PI3K pathway: S. Najib, et al.; Mol. Cell. Biol.
32, 1004 (2012),
Abstract;
Full Text
Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells: O. Mungunsukh, et al.; Am. J. Physiol. Lung Cell. Mol. Physiol.
298, L696 (2010),
Abstract;
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