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Caspase Colorimetric QUANTIPAK™

BML-AK004-0001 1 Set 395.00 USD
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Colorimetric substrates plus inhibitors to allow detection of multiple caspases. Absorbance is monitored at 405 nm.

Product Specification

Applications:Colorimetric detection, HTS
Activity assay
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Contents:1 mg each of Ac-DEVD-pNA, Ac-YVAD-pNA, Ac-IETD-pNA; 0.1 mg each of Ac-DEVD-CHO, Ac-YVAD-CHO, Ac-IETD-CHO; 1 mg p-nitroaniline.
Technical Info/Product Notes:Biocompare Article: Keep an Eye on Apoptosis with Caspase Assays
Regulatory Status:RUO - Research Use Only

Product Literature References

Indomethacin sensitizes TRAIL-resistant melanoma cells to TRAIL-induced apoptosis through ROS-mediated upregulation of death receptor 5 and downregulation of survivin: A.K. Tse, et al.; J. Invest. Dermatol. 134, 1397 (2014), Abstract;
The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction: E. Mavrommatis, et al.; Mol. Cell. Biochem. 381, 69 (2013), Abstract; Full Text
The herbal compound cryptotanshinone restores sensitivity in cancer cells that are resistant to the tumor necrosis factor-related apoptosis-inducing ligand: A.K. Tse, et al.; J. Biol. Chem. 288, 29923 (2013), Abstract; Full Text
A switch of G protein-coupled receptor binding preference from phosphoinositide 3-kinase (PI3K)-p85 to filamin A negatively controls the PI3K pathway: S. Najib, et al.; Mol. Cell. Biol. 32, 1004 (2012), Abstract; Full Text
Bleomycin induces the extrinsic apoptotic pathway in pulmonary endothelial cells: O. Mungunsukh, et al.; Am. J. Physiol. Lung Cell. Mol. Physiol. 298, L696 (2010), Abstract; Full Text

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