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Myosin monoclonal antibody (F109.3E1)

ALX-BC-1150-S-L001 1 ml 243.00 USD
ALX-BC-1150-S-L005 5 ml 801.00 USD
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Product Details

Immunogen:Both human ventricular myosin light chains.
Species reactivity:Human, Rat
Specificity:Recognizes myosin light chain 2 (LC2) (aa 45-59).
Applications:IHC (FS), WB
Recommended Dilutions/Conditions:Immunohistochemistry (frozen sections, can be used undiluted)
Western Blot (dilution 1:10)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Formulation:Sterile filtered supernatant containing 0.1% sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Regulatory Status:RUO - Research Use Only

Product Literature References

AGEs induce endothelial cells senescence and endothelial barrier dysfunction via miR-1-3p/MLCK signaling pathways: M. Cheng, et al.; Gene 851, 147030 (2023), Abstract;
Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure: M. Munkvik, et al.; PLoS One 6, e22695 (2011), Abstract; Full Text
Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells: S.P. Potta; Cell Physiol. Biochem. 25, 595 (2010), Abstract; Full Text
Differential contribution of cardiac sarcomeric proteins in the myofibrillar force response to stretch: Y. Ait Mou, et al.; Pflugers Arch. 457, 25 (2008), Abstract;
Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease: C. Chimenti, et al.; Am. J. Pathol. 172, 1482 (2008), Abstract;
Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice: O. Cazorla, et al.; Cardiovasc. Res. 69, 370 (2006), Abstract; Full Text
Cardiomyocyte stiffness in diastolic heart failure: A. Borbely, et al.; Circulation 111, 774 (2005), Abstract; Full Text
Transmural stretch-dependent regulation of contractile properties in rat heart and its alteration after myocardial infarction: O. Cazorla, et al.; FASEB J. 19, 88 (2005), Abstract; Full Text
Probing conformational changes within LC2 domains of cardiac myosin: P. Eldin, et al.; Biochemistry 33, 12558 (1994), Abstract;
Probing myosin light chain 1 structure with monoclonal antibodies: B. Cornillon, et al.; J. Mus. Res. Cell. Motility 13, 329 (1992), Abstract;

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