Synthetic peptide inhibitors that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1, VDVAD is the recognition sequence for caspase-2, DEVD is the recognition sequence for caspase-3, VEID is the recognition sequence for caspase-6, IETD is the recognition sequence for caspase-8, LEHD is the recognition sequence for caspase-9, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.
Product Specification
Recommended Dilutions/Conditions: | We recommend using 1,000x dilutions for inhibiting caspase activity in Jurkat cell culture (e.g., add 1µl to 1ml of culture medium). Optimal doses may vary for different cells and culture conditions and must be determined individually. |
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Contents: | Contains 25μl (2mM) each of the following inhibitors:
- Caspase-1 Inhibitor, Z-YVAD-FMK, yellow cap
- Caspase-2 Inhibitor, Z-VDVAD-FMK, orange cap
- Caspase-3 Inhibitor, Z-DEVD-FMK, red cap
- Caspase-6 Inhibitor, Z-VEID-FMK, violet cap
- Caspase-8 Inhibitor, Z-IETD-FMK, green cap
- Caspase-9 Inhibitor, Z-LEHD-FMK, blue cap
- Caspase-Family Inhibitor, Z-VAD-FMK, amber cap |
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Formulation: | Liquid. In DMSO. |
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Shipping: | Shipped on Blue Ice |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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