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Caspase inhibitor set III



ALX-850-227-KI01	1 Set	679.00 USD
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Synthetic peptides that irreversibly inhibit the activity of each of the caspase-family proteases. YVAD is the recognition sequence for caspase-1/ICE, VDVAD is the recognition sequence for caspase-2, DEVD is the recognition sequence for caspase-3/CPP32, WEHD is the recognition sequence for caspase-5, VEID is the recognition sequence for caspase-6/Mch2, IETD is the recognition sequence for caspase-8/FLICE, LEHD is the recognition sequence for caspase-9, and VAD is the recognition sequence for a caspase(s) that functions upstream of most other caspases.

Product Details

Recommended Dilutions/Conditions:	We recommend using 1,000x dilutions for inhibiting caspase activity in Jurkat cell culture (e.g. add 1µl to 1ml of culture medium). Optimal doses may vary for different cells and culture conditions and must be determined individually.

Contents:	Contains 25µl (2mM) each of the following inhibitors: - Caspase-1 Inhibitor, Z-YVAD-FMK, yellow cap - Caspase-2 Inhibitor, Z-VDVAD-FMK, orange cap - Caspase-3 Inhibitor, Z-DEVD-FMK, red cap - Caspase-5 Inhibitor, Z-WEHD-FMK, clear cap - Caspase-6 Inhibitor, Z-VEID-FMK, violet cap - Caspase-8 Inhibitor, Z-IETD-FMK, green cap - Caspase-9 Inhibitor, Z-LEHD-FMK, blue cap - Caspase-Family Inhibitor, Z-VAD-FMK, amber cap

Formulation:	Liquid. In DMSO.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only

Product Literature References

Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure: D.S. Pitcher, et al.; EBioMedicine 2, 642 (2015), Application(s): Cell Culture, Abstract;