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HLA-G (human) monoclonal antibody (87G) (biotin conjugate)

ALX-805-719B-C100 100 µg Biotin 792.00 USD
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Product Details

Immunogen:HLA-B27 transgenic mice were immunized with  H-2 identical murine cells transfected with expressing genes encoding HLA-G and human β2-microglobulin.
UniProt ID:P17693
Species reactivity:Human
Specificity:Recognizes membrane-bound and soluble HLA-G1 and HLA-G5.
Crossreactivity:Does not cross-react with mouse or rat HLA-G.
Applications:Flow Cytometry
Recommended Dilutions/Conditions:Flow Cytometry (1:500)
Optimal conditions must be determined individually for each application.
Purity Detail:Protein A-affinity purified.
Formulation:Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
Handling:Do not freeze. Protect from light.
Shipping:Blue Ice
Short Term Storage:+4°C
Long Term Storage:+4°C
Regulatory Status:RUO - Research Use Only

Product Literature References

A critical look at HLA-G: R. Apps, et al.; Trends Immunol. 29, 313 (2008), Abstract;
Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition: A. Ishitani, et al.; J. Immunol. 171, 1376 (2003), Abstract; Full Text
The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy: H. Wiendl, et al.; Brain 126, 176 (2003), Abstract; Full Text
HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition: B. Riteau, et al.; Int. Immunol. 13, 193 (2001), Abstract; Full Text

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HLA-G (human) monoclonal antibody (87G) 

ELISA, Flow Cytometry, IHC (FS), FUNC | Print as PDF
ALX-805-719-C100 100 µg 498.00 USD
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