Product Details
| Clone: | 87G |
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| Host: | Mouse |
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| Isotype: | IgG2a |
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| Immunogen: | HLA-B27 transgenic mice were immunized with H-2 identical murine cells transfected with expressing genes encoding HLA-G and human β2-microglobulin. |
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| UniProt ID: | P17693 |
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| Species reactivity: | Human
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| Specificity: | Recognizes membrane-bound and soluble HLA-G1 and HLA-G5. |
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| Crossreactivity: | Does not cross-react with mouse or rat HLA-G. |
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| Applications: | Flow Cytometry
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| Recommended Dilutions/Conditions: | Flow Cytometry (1:500)
Optimal conditions must be determined individually for each application. |
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| Purity Detail: | Protein A-affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.4, containing 15mM sodium azide. |
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| Handling: | Do not freeze. Protect from light. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A critical look at HLA-G: R. Apps, et al.; Trends Immunol.
29, 313 (2008),
Abstract;
Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition: A. Ishitani, et al.; J. Immunol.
171, 1376 (2003),
Abstract;
Full Text
The non-classical MHC molecule HLA-G protects human muscle cells from immune-mediated lysis: implications for myoblast transplantation and gene therapy: H. Wiendl, et al.; Brain
126, 176 (2003),
Abstract;
Full Text
HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition: B. Riteau, et al.; Int. Immunol.
13, 193 (2001),
Abstract;
Full Text
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