Product Details
| Clone: | MEM-E/08 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human HLA-E refolded with β2-microglobulin and peptide. |
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| UniProt ID: | P13747 |
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| Species reactivity: | Human
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| Specificity: | Recognizes native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. |
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| Crossreactivity: | Cross-reacts weakly with classical MHC Class I molecules HLA-A24, -B7, -B27, -B51, -B54, -C7. |
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| Applications: | Flow Cytometry, IP
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| Purity Detail: | Protein A-affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.4, containing 15mM sodium azide. |
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| Use/Stability: | Stable for at least 6 months when stored at +4°C. |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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| Shipping: | Shipped on Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis: D.K. Tennakoon, et al.; J. Immunol.
176, 7119 (2006),
Abstract;
HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines: G.L. Palmisano, et al.; Hum. Immunol.
66, 1 (2005),
Abstract;
Tissue Antigens: L. Sibilio et al.; Abstract 45 from the 3rd Int. Conference on HLA-G, Paris 62, 339 (2003),
