Product Details
| Clone: | MEM-56 |
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| Host: | Mouse |
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| Isotype: | IgG2b |
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| Immunogen: | Human thymocytes and T lymphocytes. |
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| UniProt ID: | P08575 |
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| Species reactivity: | Human
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| Applications: | Flow Cytometry
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| Purity Detail: | Protein A-affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.4, containing 0.2% BSA and 15mM sodium azide. |
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| Handling: | Do not freeze. Protect from light. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Human CD45RA is expressed on all cells of hematopoietic origin, except erythrocytes. CD45RA is a transmembrane tyrosine phosphate which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RA isoform predominates on naive/resting T cells and medullary thymocytes. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102: V. Bazil, et al.; Folia Biol (Praha)
35, 289 (1989),
Abstract;
Sialic acid-dependent epitopes of CD45 molecules of restricted cellular expression: V. Bazil, et al.; Immunogenetics
29, 202 (1989),
Abstract;
