Product Details
Alternative Name: | LFA-1, αL integrin |
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Clone: | MEM-25 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Leukocytes from a patient suffering from a LGL-type leukaemia. |
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UniProt ID: | P20701 |
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Species reactivity: | Human
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Specificity: | Recognizes the α subunit (CD11a; αL integrin) of LFA-1. |
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Applications: | Flow Cytometry, IP, FUNC
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Recommended Dilutions/Conditions: | Flow Cytometry (2µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Functional Application: blocks binding of CD54 (ICAM-1); suitable for affinity purification of LFA-1 from leukocytes. |
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Purity Detail: | Protein A-affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.4, containing 15mM (~0.1%) sodium azide. |
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Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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Shipping: | Shipped on Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Roles played by lymphocyte function-associated antigen-1 in the regulation of lymphocytic cholinergic activity.: T. Fujii et al.; Life Sci.
80, 24 (2007),
Abstract;
Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of FcgammaRII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins: L. Ottonello, et al.; Blood
93, 3505 (1999),
Abstract;
Full Text
Monoclonal antibodies against human leucocyte antigens. IV. Antibodies against subunits of the LFA-1 (CD11a/CD18) leucocyte-adhesion glycoprotein: V. Bazil, et al.; Folia Biol. (Praha)
36, 41 (1990),
Abstract;