Product Details
| Alternative Name: | CD95, APO-1, TNFRSF 6 |
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| Clone: | APO-1-1 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Human Fas (CD95; APO-1). |
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| UniProt ID: | P25445 |
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| Species reactivity: | Human
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| Applications: | Flow Cytometry
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| Formulation: | Liquid. In 1ml 50mM TRIS, pH 7.2-7.4, containing 100mM sodium chloride, 1% BSA and 0.02% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD): H. Wajant, et al.; J. Biol. Chem.
275, 24357 (2000),
Abstract;
Full Text
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L): D.C. Huang, et al.; PNAS
96, 14871 (1999),
Abstract;
Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells: F. Leithauser, et al.; Lab. Invest.
69, 415 (1993),
Abstract;
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