Product Details
Alternative Name: | ICAM-1, Intercellular adhesion molecule-1 |
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Clone: | RR1/1 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Human CD54 (ICAM-1). |
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UniProt ID: | P05362 |
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Species reactivity: | Human
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Specificity: | Recognizes the D1 domain of CD54. |
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Applications: | ELISA, Flow Cytometry, IHC (FS), WB, FUNC
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Recommended Dilutions/Conditions: | Flow Cytometry (suitable as primary antibody in staining for FACS analysis) Immunohistochemistry (stains aceton-fixed cryostat sections or cell smears. Alkaline phosphatase-anti-alkaline phosphatase (APAAP) procedure, peroxidase anti-peroxidase (PAP) procedure or the three stage immunoperoxidase technique are recommended; use at a concentration of 0.5-1.25µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~90kDa by Western blot. Functional Application: blocks adhesion of leukocytes to endothelial cells. |
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Formulation: | Liquid. In PBS, pH 7.2-7.4. |
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Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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Shipping: | Blue Ice |
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Long Term Storage: | +4°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
CD13 is a novel mediator of monocytic/endothelial cell adhesion: P. Mina-Osorio; J. Leukoc. Biol.
84, 448 (2008),
Abstract;
Full Text
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