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Chemerin monoclonal antibody (Tigy-1)

 
ALX-804-868-C100 100 µg 361.00 USD
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Product Details

Alternative Name:RARRES2, Retinoic acid receptor responder protein 2, TIG2, Tazarotene-induced gene 2 protein, RAR-responsive protein
 
Clone:Tigy-1
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Recombinant rat chemerin (aa 23-157).
 
UniProt ID:Q5BK77
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Human, Rat
 
Applications:ELISA, WB
 
Recommended Dilutions/Conditions:Western blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:Chemerin (tazarotene-induced gene 2; TIG2) is a chemotactic agent that was identified as the ligand for the orphan G protein-coupled receptor ChemR23. Chemerin has been shown to be expressed abundantly in adipose tissue and to function as a adipokine. Chemerin potentiates insulin-stimulated glucose uptake and regulates adipogenesis and adipocyte metabolism.
 
Regulatory Status:RUO - Research Use Only
 

General Literature References

Chemerin is a novel adipokine associated with obesity and metabolic syndrome: K. Bozaoglu, et al.; Endocrinology 148, 4687 (2007), Abstract;
Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism: K.B. Goralski, et al.; J. Biol. Chem. 282, 28175 (2007), Abstract; Full Text

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