Product Details
Alternative Name: | RARRES2, Retinoic acid receptor responder protein 2, TIG2, Tazarotene-induced gene 2 protein, RAR-responsive protein |
|
Clone: | Tigy-1 |
|
Host: | Mouse |
|
Isotype: | IgG2a |
|
Immunogen: | Recombinant rat chemerin (aa 23-157). |
|
UniProt ID: | Q5BK77 |
|
Source: | Purified from concentrated hybridoma tissue culture supernatant. |
|
Species reactivity: | Human, Rat
|
|
Applications: | ELISA, WB
|
|
Recommended Dilutions/Conditions: | Western blot (1:1,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
|
Purity Detail: | Protein G-affinity purified. |
|
Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
|
Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
|
Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
|
Shipping: | Blue Ice |
|
Short Term Storage: | +4°C |
|
Long Term Storage: | -20°C |
|
Scientific Background: | Chemerin (tazarotene-induced gene 2; TIG2) is a chemotactic agent that was identified as the ligand for the orphan G protein-coupled receptor ChemR23. Chemerin has been shown to be expressed abundantly in adipose tissue and to function as a adipokine. Chemerin potentiates insulin-stimulated glucose uptake and regulates adipogenesis and adipocyte metabolism. |
|
Regulatory Status: | RUO - Research Use Only |
|
General Literature References
Chemerin is a novel adipokine associated with obesity and metabolic syndrome: K. Bozaoglu, et al.; Endocrinology
148, 4687 (2007),
Abstract;
Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism: K.B. Goralski, et al.; J. Biol. Chem.
282, 28175 (2007),
Abstract;
Full Text