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IL-33 monoclonal antibody (Nessy-1) (preservative free)

ALX-804-840PF-C100 100 µg Preservative Free 457.00 USD
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Replaces Prod. #: ALX-804-840/1PF

Product Details

Alternative Name:Interleukin-33, IL-1F11, NF-HEV
Immunogen:Recombinant human IL-33 (aa 112-270) (Prod. No. ALX-522-098).
UniProt ID:O95760
Gene/Protein Identifier:90865 (Entrez GeneID), 608678 (OMIM)
Source:Purified from ascites.
Species reactivity:Human, Mouse, Rat
Specificity:Recognizes pro-IL-33 (precursor) and mature IL-33.
Applications:ELISA, IHC (PS), IP, WB
Recommended Dilutions/Conditions:Immunoprecipitation (1:100)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein G-affinity purified.
Formulation:Liquid. In PBS.
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
Shipping:Blue Ice
Short Term Storage:+4°C
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
IL-33 monoclonal antibody (Nessy-1) Immunohistochemistry
Figure: Immunohistochemical staining of endogenous human IL-33 in different human tissues (paraffin sections) using MAb to IL-33 (Nessy-1) (Prod. No. ALX-804-840). Method: Different human normal tissues (A: Stomach; B: Bronchus; C: Vulva/Anal skin; D: Nasopharynx) or cancer tissues (E: Colorectal cancer; F: Malignant glioma) were stained with MAb to lL-33 (Nessy-1) by standard immunohistochemistry. Pictures courtesy of Human Protein Atlas ("
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IL-33 monoclonal antibody (Nessy-1) Immunohistochemistry

Product Literature References

Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation: S. Stojkovic, et al.; Sci. Rep. 6, 25171 (2022), Abstract;
Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development: E. Mai, et al.; J. Transl. Med. 19, 517 (2021), Abstract;
Nuclear Interleukin-33 Is Generally Expressed in Resting Endothelium but Rapidly Lost upon Angiogenic or Proinflammatory Activation: A.M. Küchler, et al.; Am. J. Pathol. 173, 1229 (2008), Abstract;

General Literature References

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines: J. Schmitz, et al.; Immunity 23, 479 (2005), Abstract;

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