Product Specification
Alternative Name: | BR3, BlySR3, TNFRSF 13C, CD268 |
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Clone: | 7H22-E16 |
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Host: | Rat |
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Isotype: | IgG1 |
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Immunogen: | Recombinant mouse BAFF-R extracellular domain (aa 2-70). |
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UniProt ID: | Q9D8D0 |
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Source: | Purified from concentrated hybridoma tissue culture supernatant. |
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Species reactivity: | Mouse
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Applications: | Flow Cytometry, WB
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Recommended Dilutions/Conditions: | Flow Cytometry (1:100) , Western Blot (1:500) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Not recommended for immunoprecipitation. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Handling: | For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles. |
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Shipping: | Shipped on Blue Ice |
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Short Term Storage: | +4°C |
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Regulatory Status: | RUO - Research Use Only |
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Product Literature References
CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers: N.D. Huntington, et al.; Nat. Immunol.
7, 190 (2006),
Abstract;
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells: L.G. Ng, et al.; J. Immunol.
173, 807 (2004),
Abstract;
General Literature References
The BAFF/APRIL system: an important player in systemic rheumatic diseases: F. Mackay, et al.; Curr. Dir. Autoimmun.
8, 243 (2005),
Abstract;