Product Details
| Clone: | TR66 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Cloned human helper T cell line. |
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| UniProt ID: | P09693 (γ chain), P04234 (δ chain), P07766 (ε chain), P20963 (ζ chain) |
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| Source: | Purified from concentrated hybridoma tissue culture supernatant. |
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| Species reactivity: | Human
|
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| Specificity: | Recognizes the ε-chain of CD3. |
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| Applications: | Flow Cytometry, ICC, IP, WB, FUNC
|
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| Application Notes: | Detects endogenous protein by FC, ICC and IP. |
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| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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| Use/Stability: | Stable for at least 1 year after receipt when stored at -20°C. |
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| Handling: | For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells: H. Yin, et al.; Cell. Mol. Life Sci.
112, 709 (2022),
Abstract;
RIPK1 dephosphorylation and kinase activation by PPP1R3G/PP1γ promote apoptosis and necroptosis: J. Du, et al.; Nat. Commun.
12, 7067 (2021),
Abstract;
Prognostic significance of tumor-infiltrating lymphocytes in patients with operable tongue cancer: W.Y. Chen, et al.; Radiat. Oncol.
13, 157 (2018),
Abstract;
Full Text
Prognostic significance of tumor-inflitrating lymphocytes in patients with operable tongue cancer: W.Y. Chen, et al.; Radiat. Oncol.
13, 157 (2018),
Abstract;
Full Text
T cell fitness determined by signal strength: A.V. Gett, et al.; Nat. Immunol.
4, 355 (2003),
Abstract;
CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation: O. Gaide, et al.; Nat. Immunol.
3, 836 (2002),
Abstract;
T lymphocyte costimulation mediated by reorganization of membrane microdomains: A. Viola, et al.; Science
283, 680 (1999),
Abstract;
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation: T. Kataoka, et al.; J. Immunol.
161, 3936 (1998),
Abstract;
Full Text
The use of hybrid hybridomas to target human cytotoxic T lymphocytes: A. Lanzavecchia & D. Scheidegger; Eur. J. Immunol.
17, 105 (1987),
Abstract;
