Product Specification
| Alternative Name: | BR3, BlySR3, TNFRSF 13C, CD268 |
| |
| Clone: | 11C1 |
| |
| Host: | Mouse |
| |
| Isotype: | IgG1 |
| |
| Immunogen: | Mouse B cell lymphoma L1.2 cells expressing human BAFF-R. |
| |
| UniProt ID: | Q96RJ3 |
| |
| Source: | Purified from concentrated mouse hybridoma tissue culture supernatant. |
| |
| Species reactivity: | Human
|
| |
| Applications: | Flow Cytometry, IHC (FS), IHC (PS)
|
| |
| Application Notes: | Works on endogenous. |
| |
| Purity Detail: | Protein G-affinity purified. |
| |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| |
| Use/Stability: | Stable for at least 6 months after receipt when stored as recommended. |
| |
| Handling: | For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles. |
| |
| Shipping: | Shipped on Blue Ice |
| |
| Short Term Storage: | +4°C |
| |
Figure 1: Detection of endogenous BAFF-R in a human palatine tonsil paraffin section stained with the MAb to BAFF-R (human) (11C1) (Prod. No.
ALX-804-807). An intense staining of B cells follicles and weaker staining of germinal center is observed (200x)."
Please mouse over
Product Literature References
Autoantibody-producing RP105(-) B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects: S. Koarada, et al.; Rheumatology (Oxford)
49, 662 (2010),
Abstract;
Full Text
B cell-activating factor belonging to the TNF family (BAFF)-R Is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells: L.G. Ng, et al.; J. Immunol.
173, 807 (2004),
Abstract;
