Product Specification
| Alternative Name: | BR3, BlySR3, TNFRSF 13C, CD268 |
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| Clone: | 11C1 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Mouse B cell lymphoma L1.2 cells expressing human BAFF-R. |
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| UniProt ID: | Q96RJ3 |
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| Source: | Purified from concentrated mouse hybridoma tissue culture supernatant. |
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| Species reactivity: | Human
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| Applications: | Flow Cytometry, IHC (FS), IHC (PS)
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| Application Notes: | Works on endogenous. |
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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| Use/Stability: | Stable for at least 6 months after receipt when stored as recommended. |
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| Handling: | For long term storage, aliquot and freeze at -20°C. Avoid freeze/thaw cycles. |
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| Shipping: | Shipped on Blue Ice |
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| Short Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure 1: Detection of endogenous BAFF-R in a human palatine tonsil paraffin section stained with the MAb to BAFF-R (human) (11C1) (Prod. No.
ALX-804-807). An intense staining of B cells follicles and weaker staining of germinal center is observed (200x)."
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Product Literature References
Autoantibody-producing RP105(-) B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects: S. Koarada, et al.; Rheumatology (Oxford)
49, 662 (2010),
Abstract;
Full Text
B cell-activating factor belonging to the TNF family (BAFF)-R Is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells: L.G. Ng, et al.; J. Immunol.
173, 807 (2004),
Abstract;
