Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Presenilin 1 monoclonal antibody (APS 18)

ALX-804-555-C200 200 µg 529.00 USD
Do you need bulk/larger quantities?

Product Details

Clone:APS 18
Immunogen:Synthetic peptide corresponding to aa 313-334 (S313KYNAESTER
ESQDTVAENDDG334) of C-terminal human presenilin 1.
UniProt ID:P49768
Species reactivity:Human, Mouse, Rat
Crossreactivity:Does not cross-react with presenilin 2.
Applications:ELISA, ICC, WB
Recommended Dilutions/Conditions:ELISA (1µg/ml)
Immunocytochemistry (6µg/ml)
Western Blot (12µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~18kDa (C-terminal fragment) and ~46kDa (full-length) presenilin 1 by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Regulatory Status:RUO - Research Use Only
Presenilin 1 monoclonal antibody (APS 18) Immunocytochemistry
Figure: Immunocytochemistry using MAb to Presenilin 1 (APS 18) (Prod. No. ALX-804-555) shows endogenous presenilin 1 staining in Golgi and cellular vesicles in 4% paraformaldehyde fixed N2a cells."
Please mouse over
Presenilin 1 monoclonal antibody (APS 18) Immunocytochemistry

Product Literature References

Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies: A. Diehlmann, et al.; J. Neurosci. Res. 56, 405 (1999), Abstract;
Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071: B. Stahl, et al.; J. Biol. Chem. 274, 9141 (1999), Abstract;
Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation: G. Tesco, et al.; J. Biol. Chem. 273, 33909 (1998), Abstract;

Product Toolbox


Certificate of Analysis


By target:
By biological activity:
Secretase Monoclonal antibody
By catalog section:


Technical Service
Customer Service

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

All new literature pieces