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Presenilin 1 monoclonal antibody (APS 11)



ALX-804-554-C200	200 µg	743.00 USD
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Product Details

Clone:	APS 11

Host:	Mouse

Isotype:	IgG1

Immunogen:	Synthetic peptide corresponding to aa 21-34 (CH²¹LSNTVRSQND NRE³⁴) of N-terminal human presenilin 1.

UniProt ID:	P49768

Species reactivity:	Human, Mouse, Rat Primate

Crossreactivity:	Does not cross-react with presenilin 2.

Applications:	ELISA, ICC, IHC (PS), WB

Recommended Dilutions/Conditions:	ELISA (4.5µg/ml) Immunocytochemistry (0.75µg/ml) Immunohistochemistry (paraffin sections, 0.75µg/ml) Western Blot (12µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Application Notes:	Detects a band of ~28kDa by Western blot.

Purity Detail:	Protein G-affinity purified.

Formulation:	Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.

Handling:	Avoid freeze/thaw cycles.

Shipping:	Blue Ice

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only

Presenilin 1 monoclonal antibody (APS 11) Immunocytochemistry

Figure: Immunocytochemistry on mouse fibroblast cell line stained with MAb to presenilin 1 (APS 11) (Prod. No. ALX-804-554)."

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Product Literature References

Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies: A. Diehlmann, et al.; J. Neurosci. Res. 56, 405 (1999), Abstract;