| Alternative Name: | OPG, TNFRSF 11B, Osteoclastogenesis inhibitory factor |
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| Clone: | OPG-01 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Recombinant human OPG (osteoprotegerin). |
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| UniProt ID: | O00300 |
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| Species reactivity: | Human
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| Applications: | ELISA, WB
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Lyophilized from sterile filtered solution in 0.05M phosphate buffer, pH 7.2, containing 0.1M sodium chloride. |
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| Reconstitution: | Reconstitute with 100µl distilled water. Activity is not affected by slight turbidity. Clarify by centrifugation. |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Osteoprotegerin (OPG) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 aa with molecular weight of 55kDa as a monomer and 110kDa as a disulfide-linked dimer. It acts as a soluble factor in the regulation of bone mass and may be beneficial in the treatment of osteoporosis associated with increased osteoclast activity. |
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| Regulatory Status: | RUO - Research Use Only |
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| Manufacturer: | Manufactured by BioVendor. |
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