Product Specification
Alternative Name: | TLR3, CD283 |
|
Clone: | TLR3.7 |
|
Host: | Mouse |
|
Isotype: | IgG1 |
|
Immunogen: | Recombinant human TLR3 (Toll-like receptor 3). |
|
UniProt ID: | O15455 |
|
Source: | Purified from hybridoma tissue culture supernatant. |
|
Species reactivity: | Human
|
|
Applications: | Flow Cytometry, ICC, IP, FUNC
|
|
Application Notes: | Functional Application: blocks double-stranded RNA-mediated signalling |
|
Formulation: | Liquid. Purified antibody in PBS containing 10% glycerol. Does not contain any preservatives. |
|
Use/Stability: | Stable for at least 1 year after receipt when stored as recommended. |
|
Handling: | Avoid freeze/thaw cycles. |
|
Shipping: | Shipped on Blue Ice |
|
Long Term Storage: | -20°C |
|
Regulatory Status: | RUO - Research Use Only |
|
Figure: Clone TLR3.7 inhibits dsRNA-induced IFN-b production by MRC-5 cells.
Figure: Immunoprecipitation of human TLR3 in transfectants with clone TLR3.7.
Figure: FC with clone TLR3.7.
Please mouse over
Product Literature References
Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains: M. Tanabe, et al.; BBRC
311, 39 (2003),
Abstract;
Subcellular localization of Toll-like receptor 3 in human dendritic cells: M. Matsumoto, et al.; J. Immunol.
171, 3154 (2003),
Abstract;
Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling: M. Matsumoto, et al.; BBRC
293, 1364 (2002),
Abstract;