Product Details
| Clone: | 196C429 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Synthetic peptide corresponding to aa 335-350 of human HtrA2/Omi. |
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| UniProt ID: | O43464 |
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| Species reactivity: | Human
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| Applications: | IHC, WB
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| Recommended Dilutions/Conditions: | Western Blot (2-3µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Application Notes: | Detects bands of ~38kDa and ~50kDa by Western blot. |
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| Purity Detail: | Protein G-affinity purified. |
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| Formulation: | Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide. |
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| Shipping: | Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Figure 1: Immunohistochemistry using MAb to HtrA2/Omi (human) (196C429) (Prod. No.
ALX-804-427) shows cytoplasmic staining in stomach tumor tissue (A) and very weak staining in normal stomach tissue (B)."
Figure 2: Western blot detection of Omi/HtrA2 in HL-60cell lysate. Two protein bands of approximate molecular weight of 50 and 38kDa was detected using
ALX-804-427 at 2µg/ml dilution. The two bands may represent precursor and mature form of Omi/Htra2, respectively."
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Product Literature References
Apoptotic death concurrent with CD3 stimulation in primary human CD8+ T lymphocytes: a role for endogenous granzyme B: M. Laforge, et al.; J. Immunol.
176, 3966 (2006),
Abstract;
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia: X. Wang, et al.; Neurobiol. Dis.
16, 179 (2004),
Abstract;
Immunohistochemical analysis of Omi/HtrA2 expression in stomach cancer: S.H. Lee, et al.; APMIS
111, 586 (2003),
Abstract;
