Product Details
Alternative Name: | TLR6, CD286 |
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Clone: | 86B1153.2 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Synthetic peptide corresponding to aa 408-424 in the cytoplasmic portion of human TLR6 (Toll-like receptor 6). |
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UniProt ID: | Q9Y2C9 |
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Species reactivity: | Human
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Applications: | Flow Cytometry, IHC
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Recommended Dilutions/Conditions: | Flow Cytometry (intracellular, 0.5-5µg per 106 cells) Immunohistochemistry (paraffin sections, 5µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Flow Cytometry: Suitable for cell surface and intracellular FC. |
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Positive Control: | Ramos cells can be used as positive control. |
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Purity Detail: | Protein G-affinity purified. |
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Formulation: | Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide. |
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Use/Stability: | Stable for at least 6 months when stored at +4°C. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Short Term Storage: | +4°C |
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Long Term Storage: | -20°C |
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Regulatory Status: | RUO - Research Use Only |
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Figure: Intracellular flow cytometry of TLR6 (shaded peak) and mouse IgG1 isotype control (open peak) in 10
6 Ramos cells using 3µg of MAb to TLR6 (Prod. No.
ALX-804-363)."
Figure: Immunohistochemical analysis of TLR6 in paraffin-embedded formalin-fixed human liver tissue using an isotype control (top) or MAb to TLR6 (Prod. No.
ALX-804-363) at 5μg/ml."
Immunohistochemistry analysis: Formalin-fixed, paraffin-embedded tonsil probed with Toll-like receptor 6 (human), mAb (86B1153.2) at 5µg/ml.
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Product Literature References
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils: C.K. Wong, et al.; Am. J. Respir. Cell Mol. Biol.
37, 85 (2007),
Abstract;
Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus: G. Hajishengallis, et al.; Cell Microbiol.
8, 1557 (2006),
Abstract;
Toll-like receptor 2-mediated human B cell differentiation: L.M. Ganley-Leal, et al.; Clin. Immunol.
120, 272 (2006),
Abstract;
Evidence of Toll-like receptor molecules on human platelets: F. Cognasse, et al.; Immunol. Cell Biol.
83, 196 (2005),
Abstract;
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