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Toll-like receptor 3 monoclonal antibody (40C1285.6) (R-PE conjugate)

ALX-804-362R-C100 100 µg R-PE 668.00 USD
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Product Details

Alternative Name:TLR3, CD283
Immunogen:Synthetic peptide corresponding to aa 55-70 (VLNLTHNQLRRLPAAN) of human TLR3 (Toll-like receptor 3) cytoplasmic portion.
UniProt ID:O15455
Species reactivity:Human, Mouse
Applications:Flow Cytometry, ICC
Recommended Dilutions/Conditions:Flow Cytometry (cell surface, intracellular)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein G-affinity purified.
Formulation:Liquid. In PBS containing 0.05% sodium azide.
Handling:Do not freeze. Protect from light.
Shipping:Blue Ice
Short Term Storage:+4°C
Long Term Storage:+4°C
Regulatory Status:RUO - Research Use Only

Product Literature References

Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain: C.T. Ranjith-Kumar, et al.; J. Biol. Chem. 282, 7668 (2007), Abstract; Full Text
Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells: C.T. Ranjith-Kumar, et al.; J. Biol. Chem. 282, 17696 (2007), Abstract; Full Text
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils: C.K. Wong, et al.; Am. J. Respir. Cell Mol. Biol. 37, 85 (2007), Abstract;
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes: K. Li, et al.; J. Biol. Chem. 280, 16739 (2005), Abstract; Full Text
Regulation of the polymeric Ig receptor by signaling through TLRs 3 and 4: linking innate and adaptive immune responses: T.A. Schneeman, et al.; J. Immunol. 175, 376 (2005), Abstract;
Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto’s autoimmune thyroiditis: N. Harii, et al.; Mol. Endocrinol. 19, 1231 (2005), Abstract;
Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria: E. Furrie, et al.; Immunology 115, 565 (2005), Abstract;
The effect of innate immunity on autoimmune diabetes and the expression of Toll-like receptors on pancreatic islets: L. Wen, et al.; J. Immunol. 172, 3173 (2004), Abstract;
Subcellular localization of Toll-like receptor 3 in human dendritic cells: M. Matsumoto, et al.; J. Immunol. 171, 3154 (2003), Abstract;

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Toll-like receptor 3 monoclonal antibody (40C1285.6) 

Flow Cytometry, ICC, IHC (PS), IP, WB | Print as PDF
ALX-804-362-C100 100 µg 510.00 USD
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